Faculty Profiles - HORISAWA KENICHI (2024)

Transcription factor-mediated direct cellular reprogramming yields cell-type specific DNA methylation signatureReviewedInternational journal

Kenichi Horisawa Shizuka Miura Hiromitsu Araki Fumihito Miura Takashi Ito Atsushi Suzuki

Scientific Reports 13 ( 1 ) 22317 2023.12

Direct Conversion of Human Endothelial Cells Into Liver Cancer-Forming Cells Using Nonintegrative Episomal VectorsReviewedInternational journal

#Takeshi Goya,@Kenichi Horisawa,@Miyako Udono,@Yasuyuki Ohkawa,@Yoshihiro Ogawa,@Sayaka Sekiya,@Atsushi Suzuki

Hepatology communications 2022.2

Direct reprogramming of human umbilical vein- and peripheral blood-derived endothelial cells into hepatic progenitor cells.InvitedReviewedInternational journal

#Inada H., Udono M., Matsuda-Ito K., Horisawa K., Ohkawa Y., Miura S., Goya T., #Yamamoto J., @Nagasaki M., @Ueno K., Saitou D., Suyama M., Maehara Y., Kumamaru W., Ogawa Y., Sekiya S., Suzuki A.

Nat comm 11 2020.12

The Dynamics of Transcriptional Activation by Hepatic Reprogramming Factors.ReviewedInternational journal

Horisawa K., Udono M., @Ueno K., Ohkawa Y., @Nagasaki M., Sekiya S., Suzuki A.

Mol Cell 79 660 - 676 2020.8

Generation of Nanog reporter mice that distinguish pluripotent stem cells from unipotent primordial germ cellsInvitedReviewedInternational journal

#Terada, Maiko; Kawamata, Masaki; #Kimura, Ryota; Sekiya, Sayaka; Nagamatsu, Go; Hayashi, Katsuhiko; Horisawa, Kenichi; Suzuki, Atsushi

GENESIS 57 ( 11-12 ) 2019.11

Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors.ReviewedInternational journal

Takashima Y, Horisawa K, Udono M, Ohkawa Y, Suzuki A.

Cancer Sci. 109 ( 11 ) 3543 - 3553 2018.11

Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinoma.InvitedReviewedInternational journal

Sci Rep. 6 34691 - 34691 2016.10

Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation.ReviewedInternational journal

@Niikura K, Horisawa K, @Doi N

J Biochem. 159 ( 1 ) 123 - 132 2016.1

A fusogenic peptide from a sea urchin fertilization protein promotes intracellular delivery of biomacromolecules by facilitating endosomal escape.ReviewedInternational journal

@Niikura K, Horisawa K, @Doi N

J Control Release 212 85 - 93 2015.8

Electrochemical detection of tyrosine derivatives and protein tyrosine kinase activity using boron-doped diamond electrodesReviewedInternational journal

@Chiku M., Horisawa K., @Doi N., @Yanagawa H., @Einaga Y.

BIOSENSORS & BIOELECTRONICS 26 ( 1 ) 235 - 240 2010.9

3 '-Untranslated region of doublecortin mRNA is a binding target of the Musashi1 RNA-binding proteinReviewedInternational journal

Horisawa K., @Imai T., @Okano H., @Yanagawa H.

FEBS LETTERS 583 ( 14 ) 2429 - 2434 2009.7

Use of cDNA Tiling Arrays for Identifying Protein Interactions Selected by In Vitro Display TechnologiesReviewedInternational journal

Horisawa K., @Doi N., @Yanagawa H.

PLOS ONE 3 ( 2 ) 2008.2

Affinity selection of DNA-binding protein complexes using mRNA displayReviewedInternational journal

@Tateyama S., Horisawa K., @Takashima H., @Miyamoto-Sato E., @Doi N., @Yanagawa H.

NUCLEIC ACIDS RESEARCH 34 ( 3 ) 2006.2

Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexesReviewedInternational journal

@Miyamoto-Sato E., @Ishizaka M., Horisawa K., @Tateyama S., @Takashima H., @Fuse S., @Sue K., @Hirai N., @Masuoka K., @Yanagawa H.

GENOME RESEARCH 15 ( 5 ) 710 - 717 2005.5

Application of quantitative real-time PCR for monitoring the process of enrichment of clones on in vitro protein selectionReviewedInternational journal

Horisawa K., @Doi N., @Takashima H., @Yanagawa H.

JOURNAL OF BIOCHEMISTRY 137 ( 2 ) 121 - 124 2005.2

In vitro selection of Jun-associated proteins using mRNA displayReviewedInternational journal

Horisawa K., @Tateyama S., @Ishizaka M., @Matsumura N., @Takashima H., @Miyamoto-Sato E., @Doi N., @Yanagawa H.

NUCLEIC ACIDS RESEARCH 32 ( 21 ) 2004.12

Highly stable and efficient mRNA templates for mRNA-protein fusions and C-terminally labeled proteinsReviewedInternational journal

@Miyamoto-Sato E., @Takashima H., @Fuse S., @Sue K., @Ishizaka M., @Tateyama S., @Horisawa K., @Sawasaki T., @Endo Y., @Yanagawa H.

NUCLEIC ACIDS RESEARCH 31 ( 15 ) 2003.8

PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast CancerReviewedInternational journal

@Takehiro Yamamoto @Tetsu Hayashida @Yohei Masugi @Kiyotaka Oshikawa @Noriyo Hayakawa @Mai Itoh @Chiyoko Nishime @Masami Suzuki @Aiko Nagayama @Yuko Kawai @Takako Hishiki @Tomomi Matsuura @Yoshiko Naito @Akiko Kubo @Arisa Yamamoto @Yujiro Yoshioka @Tomokazu Kurahori @Misa Nagasaka @Minako Takizawa @Naoharu Takano @Koji Kawakami @Michiie Sakamoto @Masatoshi Wakui @Takushi Yamamoto @Yuko Kitagawa @Yasuaki Kabe Kenichi Horisawa Atsushi Suzuki @Masaki Matsumoto @Makoto Suematsu

Cancer Research 84 ( 7 ) 1065 - 1083 2024.4

Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis.InvitedReviewedInternational journal

@Horisawa-Takada Y., @Kodera C., @Takemoto K., @Sakash*ta A., Horisawa K., @Maeda R., @Shimada R., @Usuki S., @Fujimura S., @Tani N., @Matsuura K., @Akiyama T., Suzuki A., @Niwa H., @Tachibana M., @Ohba T., @Katabuchi H., @Namekawa S., @Araki K., @Ishiguro K.

Nat comm 12 ( 1 ) 2021.6

In vitro selection of bispecific diabody fragments using covalent bicistronic DNA display.ReviewedInternational journal

@Nakayama M, @Komiya S, @Fujiwara K, Horisawa K, @Doi N

Biochem Biophys Res Commun. 478 ( 2 ) 606 - 611 2016.9

PURE mRNA display for in vitro selection of single-chain antibodies.ReviewedInternational journal

@Nagumo Y, @Fujiwara K, Horisawa K, @Yanagawa H, @Doi N

J Biochem. 5 ( 159 ) 519 - 526 2016.5

Development of μtas for high-throughput screening of nad(p)-dependent oxidoreductases.ReviewedInternational journal

@Shimokihara S,　@sh*tara S,　@Oyobiki R,　@Watanabe T,　@Einaga Y,　@Matsumoto Y,　@Fujiwara K,　Horisawa K,　@Doi N

1302 - 1304 2015.10

Toward high-throughput screening of NAD(P)-dependent oxidoreductases using boron-doped diamond microelectrodes and microfluidic devices.ReviewedInternational journal

@Oyobiki R, @Kato T, @Katayama M, @Sugitani A, @Watanabe T, @Einaga Y, @Matsumoto Y, Horisawa K, @Doi N

Anal Chem. 86 ( 19 ) 9570 - 9575 2014.10

Structural basis for inhibition of the MDM2:p53 interaction by an optimized MDM2-binding peptide selected with mRNA display.ReviewedInternational journal

@Nagata T, @Shirakawa K, @Kobayashi N, @Shiheido H, @Tabata N, @Sakuma-Yonemura Y, Horisawa K, @Katahira M, @Doi N, @Yanagawa H

PLoS One. 9 ( 10 ) e109163 - e109163 2014.10

MIP-2A Is a Novel Target of an Anilinoquinazoline Derivative for Inhibition of Tumour Cell ProliferationReviewedInternational journal

@Tokunaga M., @Shiheido H., @Tabata N., @Sakuma-Yonemura Y., @Takashima H., Horisawa K., @Doi N., @Yanagawa H.

PLOS ONE 8 ( 9 ) 2013.9

Hereditary Spastic Paraplegia Protein Spartin Is an FK506-Binding Protein Identified by mRNA DisplayReviewedInternational journal

@Tokunaga M., @Shiheido H., @Hayakawa I., @Utsumi A., @Sakuma-Yonemura Y., @Tabata N., @Takashima H., @Doi N., Horisawa K., @Sakuma-Yonemura Y., @Tabata N., @Yanagawa H.

CHEMISTRY & BIOLOGY 20 ( 7 ) 935 - 942 2013.7

DNA Display Selection of Peptide Ligands for a Full-Length Human G Protein-Coupled Receptor on CHO-K1 CellsReviewedInternational journal

@Doi N., @Yamakawa N., @Matsumoto H., @Yamamoto Y., @Nagano T., @Matsumura N., Horisawa K., @Yanagawa H.

PLOS ONE 7 ( 1 ) 2012.1

Construction of glomerular epithelial cells in vitro for removal of immune complexReviewedInternational journal

@Wang PC., Horisawa K., @Matsumura M.

Journal of Artificial Organs 2 170 - 175 1999.9

免疫複合体の除去能を強化した腎糸球体上皮細胞の構築Reviewed

@王碧昭, @堀澤健一, @高躍華, @松村正利

人工臓器 28 11 - 14 1999.2

免疫複合体の除去に効果的な培養細胞腎糸球体上皮細胞の構築：人工腎臓への新しい試みInvitedReviewed

@王碧昭, @堀澤健一, @高躍華, @松村正利, @沖垣達

重井医学年報 19 13 - 19 1997.10